Managers are separated into 3 Tiers:
The harder the Card is to find the more powerful the Manager. The more you Upgrade your Managers the more Powerful they become.
In the case of El Patron, his Getaway power doubles at the next level.
Products, like Managers, as they are Upgraded their Sell Value increases which earns you more Profit from the Market.
There are also Sicario Cards which you Unlock like the aforementioned Character & Manager Cards (collecting Replicate Cards) with the chief difference being these are your only Characters & Managers which can represent you in Fight Mode! Some will be familiar as they can do double duty both Managing your business areas and Fighting for you.
The Sicario Cards can grant you Special Boosts like Speed & Profit but not all of these have specializations beneficial to your operations other than the Fight Mode ability i.e. Workbenches, Storeroom etc.. . If they possess a Boost for your other operations it will be indicated in the top left corner of the Characters Image on the Card itself, indicated by the Red Box, with the effective Boost rate listed on the bar on the bottom of Card.
How The Sicario Cards differ from their Manager & Character colleagues is they have:
(A) Fight Power
(B) Health Points
(C) Focus Fire Boost
which are all used in the Fight Mode game.